BDBM50211030 CHEMBL232867::methyl 2-(4-acetylphenyl)cyclopent-1-enecarboxylate

SMILES COC(=O)C1=C(CCC1)c1ccc(cc1)C(C)=O

InChI Key InChIKey=LGPCFMYKDFHTOT-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50211030   

TargetSodium-dependent dopamine transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211030(methyl 2-(4-acetylphenyl)cyclopent-1-enecarboxylat...)
Affinity DataKi:  4.90E+4nMAssay Description:Inhibition of [3H]DA uptake in human DAT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211030(methyl 2-(4-acetylphenyl)cyclopent-1-enecarboxylat...)
Affinity DataKi:  2.40E+5nMAssay Description:Displacement of [125I]RTI55 from human NET expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211030(methyl 2-(4-acetylphenyl)cyclopent-1-enecarboxylat...)
Affinity DataKi:  2.96E+5nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211030(methyl 2-(4-acetylphenyl)cyclopent-1-enecarboxylat...)
Affinity DataKi:  3.35E+5nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211030(methyl 2-(4-acetylphenyl)cyclopent-1-enecarboxylat...)
Affinity DataKi:  6.46E+5nMAssay Description:Inhibition of [3H]DA uptake in human NET expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211030(methyl 2-(4-acetylphenyl)cyclopent-1-enecarboxylat...)
Affinity DataKi:  1.16E+6nMAssay Description:Inhibition of [3H]SER uptake in human SERT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed