BDBM50215427 CHEMBL243318::N-(4-(aminomethyl)benzyl)-2-(6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-2-oxopyrazin-1(2H)-yl)acetamide

SMILES NCc1ccc(CNC(=O)Cn2c(c(Cl)nc(NC3CCC3)c2=O)-c2cccc(N)c2)cc1

InChI Key InChIKey=MMGDHPDFKPQSQJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50215427   

TargetCoagulation factor VII(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215427(CHEMBL243318 | N-(4-(aminomethyl)benzyl)-2-(6-(3-a...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215427(CHEMBL243318 | N-(4-(aminomethyl)benzyl)-2-(6-(3-a...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215427(CHEMBL243318 | N-(4-(aminomethyl)benzyl)-2-(6-(3-a...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed