BDBM50215758 2-((2-aminopyridin-4-yl)methylamino)-N-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)benzamide::CHEMBL400109

SMILES Nc1cc(CNc2ccccc2C(=O)Nc2ccc3OC(F)(F)Oc3c2)ccn1

InChI Key InChIKey=COXZTUCUTWYLEP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50215758   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215758(2-((2-aminopyridin-4-yl)methylamino)-N-(2,2-difluo...)
Affinity DataIC50:  634nMAssay Description:Inhibition of b-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215758(2-((2-aminopyridin-4-yl)methylamino)-N-(2,2-difluo...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215758(2-((2-aminopyridin-4-yl)methylamino)-N-(2,2-difluo...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215758(2-((2-aminopyridin-4-yl)methylamino)-N-(2,2-difluo...)
Affinity DataIC50:  634nMAssay Description:Inhibition of b-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed