BDBM50218116 CHEMBL244403::naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone
SMILES CCCCCOc1ccc(C(=O)c2cccc3ccccc23)c2ccccc12
InChI Key InChIKey=RSUMDJRTAFBISX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 20 hits for monomerid = 50218116
Affinity DataKi: 19nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Displacement of [3H]-CP55,940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
TargetCytochrome P450 2E1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of CYP2E1 in human liver microsomesMore data for this Ligand-Target Pair
TargetCytochrome P450 2C8(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of CYP2C8 in human liver microsomesMore data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 8.08E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of rat CB1 receptorMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 73nMAssay Description:Agonist activity at human CB1 receptor expressed in HEK293 cells assessed as [35S]GTPgamma bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30E+3nMAssay Description:Displacement of [3H]CP55940 from membrane bound human CB2 receptor after 1 hr by beta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 6.10nMAssay Description:Agonist activity at human CB1 receptor expressed in HEK293 cells assessed as reversal of forskolin-evoked cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 72nMAssay Description:Agonist activity at human CB1 receptor expressed in HEK293 EBNA cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.58E+3nMAssay Description:Displacement of [3H]SR141716A from membrane bound human CB1 receptor after 1 hr by beta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 28nMAssay Description:Agonist activity at human CB2 receptor expressed in CHOK1 cells assessed as reversal of forskolin-evoked cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair