BDBM50218706 CHEMBL429819::methyl [3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepin-8-yl]acetate

SMILES COC(=O)Cc1ccc2Nc3cc(ccc3C(=O)Nc2c1)-c1ccc(N)c(OC)c1

InChI Key InChIKey=UKFROVUCAJTDIC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50218706   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218706(CHEMBL429819 | methyl [3-(3-methoxy-4-nitrophenyl)...)
Affinity DataEC50:  890nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218706(CHEMBL429819 | methyl [3-(3-methoxy-4-nitrophenyl)...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed