BDBM50219363 3-(2-(3,5-difluorobenzyl)-1H-benzo[d]imidazol-5-yl)-1-((1r,4r)-4-morpholinocyclohexyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL438344

SMILES Nc1ncnc2n(nc(-c3ccc4nc(Cc5cc(F)cc(F)c5)[nH]c4c3)c12)[C@H]1CC[C@@H](CC1)N1CCOCC1

InChI Key InChIKey=GFADMHPWADYGAH-HZCBDIJESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50219363   

TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219363(3-(2-(3,5-difluorobenzyl)-1H-benzo[d]imidazol-5-yl...)
Affinity DataIC50:  152nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219363(3-(2-(3,5-difluorobenzyl)-1H-benzo[d]imidazol-5-yl...)
Affinity DataIC50:  183nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed