BDBM50220276 (2S)-9-(4-chlorophenylsulfonyl)-9-aza-bicyclo[3.3.1]nonan-2-yl 4-ethyl-4-hydroxypiperidine-1-carboxylate::CHEMBL236196

SMILES CCC1(O)CCN(CC1)C(=O)O[C@H]1CCC2CCCC1N2S(=O)(=O)c1ccc(Cl)cc1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220276   

TargetAmyloid-beta precursor protein(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50220276((2S)-9-(4-chlorophenylsulfonyl)-9-aza-bicyclo[3.3....)
Affinity DataIC50: 104nMAssay Description:Inhibition of gamma-secretase assessed as reduction of membrane A-beta-40 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed