BDBM50221251 4-(4,5-dihydro-5-thioxo-1,3,4-thiadiazol-2-yl)-1-[alpha-(4-hydroxy-3-methoxyphenyl)methylene]semicarbazide::CHEMBL235471

SMILES COc1cc(C=NNC(=O)Nc2nnc(S)s2)ccc1O

InChI Key InChIKey=QHSNHXYQPCGNTR-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50221251   

TargetCarbonic anhydrase 9(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50221251(4-(4,5-dihydro-5-thioxo-1,3,4-thiadiazol-2-yl)-1-[...)
Affinity DataKi:  2.60E+4nMAssay Description:Inhibition of catalytic domain of human cloned carbonic anhydrase9 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50221251(4-(4,5-dihydro-5-thioxo-1,3,4-thiadiazol-2-yl)-1-[...)
Affinity DataKi:  5.16E+4nMAssay Description:Inhibition of human cloned carbonic anhydrase1 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Assiut University

Curated by ChEMBL
LigandPNGBDBM50221251(4-(4,5-dihydro-5-thioxo-1,3,4-thiadiazol-2-yl)-1-[...)
Affinity DataKi:  3.86E+5nMAssay Description:Inhibition of human cloned carbonic anhydrase2 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed