BDBM50221673 CHEMBL394292::N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}-4-ethynylbenzamide

SMILES Clc1cccc(N2CCN(CCCCNC(=O)c3ccc(cc3)C#C)CC2)c1Cl

InChI Key InChIKey=WOZSFGJKUOKIMV-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50221673   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50221673(CHEMBL394292 | N-{4-[4-(2,3-dichlorophenyl)piperaz...)
Affinity DataKi:  0.310nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50221673(CHEMBL394292 | N-{4-[4-(2,3-dichlorophenyl)piperaz...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine receptor D2 long expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50221673(CHEMBL394292 | N-{4-[4-(2,3-dichlorophenyl)piperaz...)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine receptor D2 short expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Sus scrofa)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50221673(CHEMBL394292 | N-{4-[4-(2,3-dichlorophenyl)piperaz...)
Affinity DataKi:  910nMAssay Description:Displacement of [3H]SCH 23390 from pig dopamine D1 receptor in porcine striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50221673(CHEMBL394292 | N-{4-[4-(2,3-dichlorophenyl)piperaz...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in CHO dhfr mutant cells assessed as stimulation of mitogenesis after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed