BDBM50222290 3'-chloro-7,8-dihydroxyisoflavone::CHEMBL241815::IR-308

SMILES Oc1ccc2c(occ(-c3cccc(Cl)c3)c2=O)c1O

InChI Key InChIKey=KGASEMKSFXQPPD-UHFFFAOYSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50222290   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Homo sapiens (Human))
Universidad De Santiago

LigandPNGBDBM50222290(3'-chloro-7,8-dihydroxyisoflavone | CHEMBL241815 |...)
Affinity DataIC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The reactions were done in a volume of 2 mL and constantly stirred using a magnetic stir bar at room temperature (23 °C). Reactions with the crude, a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universidad De Santiago

LigandPNGBDBM50222290(3'-chloro-7,8-dihydroxyisoflavone | CHEMBL241815 |...)
Affinity DataIC50:  300nMpH: 7.3 T: 2°CAssay Description:The reactions were done in a volume of 2 mL and constantly stirred using a magnetic stir bar at room temperature (23 °C). Reactions with the crude, a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Chongqing University

Curated by ChEMBL
LigandPNGBDBM50222290(3'-chloro-7,8-dihydroxyisoflavone | CHEMBL241815 |...)
Affinity DataEC50:  3.68E+4nMAssay Description:Inhibition of PI3Kalpha H1047R mutant (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM50222290(3'-chloro-7,8-dihydroxyisoflavone | CHEMBL241815 |...)
Affinity DataIC50:  780nMAssay Description:Inhibition of 12-hLOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM50222290(3'-chloro-7,8-dihydroxyisoflavone | CHEMBL241815 |...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of 15-hLO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Homo sapiens (Human))
Universidad De Santiago

LigandPNGBDBM50222290(3'-chloro-7,8-dihydroxyisoflavone | CHEMBL241815 |...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of 15-hLO2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed