BDBM50223968 8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl cyclohexylmethyl(thiophen-3-yl)carbamate::CHEMBL393736

SMILES CN1C2CCC1CC(C2)OC(=O)N(CC1CCCCC1)c1ccsc1

InChI Key InChIKey=FHNLUXLINNMPIP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50223968   

TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50223968(8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl cyclohexyl...)
Affinity DataIC50:  109nMAssay Description:Antagonist activity at cloned muscarinic M3 receptor expressed in CHO cells by measuring calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50223968(8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl cyclohexyl...)
Affinity DataIC50:  271nMAssay Description:Antagonist activity at cloned muscarinic M2 receptor expressed in CHO cells by measuring calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50223968(8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl cyclohexyl...)
Affinity DataIC50:  126nMAssay Description:Antagonist activity at cloned muscarinic M1 receptor expressed in CHO cells by measuring calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed