BDBM50223977 8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl 4-methoxybenzyl(phenyl)carbamate::CHEMBL429270

SMILES COc1ccc(CN(C(=O)OC2CC3CCC(C2)N3C)c2ccccc2)cc1

InChI Key InChIKey=CNDOHBNSSCZYEQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50223977   

TargetMuscarinic acetylcholine receptor M1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50223977(8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl 4-methoxyb...)
Affinity DataIC50: 734nMAssay Description:Antagonist activity at cloned muscarinic M1 receptor expressed in CHO cells by measuring calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50223977(8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl 4-methoxyb...)
Affinity DataIC50: 776nMAssay Description:Antagonist activity at cloned muscarinic M3 receptor expressed in CHO cells by measuring calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50223977(8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl 4-methoxyb...)
Affinity DataIC50: 1.36E+3nMAssay Description:Antagonist activity at cloned muscarinic M2 receptor expressed in CHO cells by measuring calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed