BDBM50223986 8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl (5-methylthiophen-2-yl)methyl(phenyl)carbamate::CHEMBL236451

SMILES CN1C2CCC1CC(C2)OC(=O)N(Cc1ccc(C)s1)c1ccccc1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50223986   

TargetMuscarinic acetylcholine receptor M3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50223986(8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl (5-methylt...)
Affinity DataIC50: 262nMAssay Description:Antagonist activity at cloned muscarinic M3 receptor expressed in CHO cells by measuring calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50223986(8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl (5-methylt...)
Affinity DataIC50: 410nMAssay Description:Antagonist activity at cloned muscarinic M2 receptor expressed in CHO cells by measuring calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50223986(8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl (5-methylt...)
Affinity DataIC50: 518nMAssay Description:Antagonist activity at cloned muscarinic M1 receptor expressed in CHO cells by measuring calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed