BDBM50224366 1-(2-chloro-2-phenylethyl)-N-(3-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL238774

SMILES ClC(Cn1ncc2c(Nc3cccc(Cl)c3)ncnc12)c1ccccc1

InChI Key InChIKey=NZWFYGUFULGMCI-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50224366   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50224366(1-(2-chloro-2-phenylethyl)-N-(3-chlorophenyl)-1H-p...)
Affinity DataKi:  240nMAssay Description:Inhibition human recombinant Abl using Abtide peptide substrate in presence of [gamma-32P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50224366(1-(2-chloro-2-phenylethyl)-N-(3-chlorophenyl)-1H-p...)
Affinity DataKi:  1.71E+3nMAssay Description:Inhibition human recombinant cSRC using KVEKIGEGTYGVVYK peptide substrate in presence of [gamma-32P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50224366(1-(2-chloro-2-phenylethyl)-N-(3-chlorophenyl)-1H-p...)
Affinity DataKi:  3.80E+3nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed