BDBM50226246 6-(2-phenethyl-1,2,3,4-tetrahydroisoquinolin-7-yloxy)nicotinamide::CHEMBL237072

SMILES NC(=O)c1ccc(Oc2ccc3CCN(CCc4ccccc4)Cc3c2)nc1

InChI Key InChIKey=IZPIYLICUYIVEI-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50226246   

TargetMu-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50226246(6-(2-phenethyl-1,2,3,4-tetrahydroisoquinolin-7-ylo...)
Affinity DataKi: >3.33E+3nMAssay Description:Displacement of [3H]diprenorphine from cloned human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50226246(6-(2-phenethyl-1,2,3,4-tetrahydroisoquinolin-7-ylo...)
Affinity DataKi:  3.61E+3nMAssay Description:Displacement of [3H]diprenorphine from cloned human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50226246(6-(2-phenethyl-1,2,3,4-tetrahydroisoquinolin-7-ylo...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]bremazocine from cloned human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed