BDBM50226258 6-(2-phenethylisoindolin-5-yloxy)nicotinamide::CHEMBL235154

SMILES NC(=O)c1ccc(Oc2ccc3CN(CCc4ccccc4)Cc3c2)nc1

InChI Key InChIKey=ACAQNMZIFFSQCU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50226258   

TargetMu-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50226258(6-(2-phenethylisoindolin-5-yloxy)nicotinamide | CH...)
Affinity DataKi:  659nMAssay Description:Displacement of [3H]diprenorphine from cloned human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50226258(6-(2-phenethylisoindolin-5-yloxy)nicotinamide | CH...)
Affinity DataKi:  2.27E+3nMAssay Description:Displacement of [3H]bremazocine from cloned human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50226258(6-(2-phenethylisoindolin-5-yloxy)nicotinamide | CH...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]diprenorphine from cloned human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed