BDBM50227742 3-(2-methyl-4-(3-((2-methyl-4-(trifluoromethyl)benzamido)methyl)phenoxy)phenyl)propanoic acid::CHEMBL237730

SMILES Cc1cc(Oc2cccc(CNC(=O)c3ccc(cc3C)C(F)(F)F)c2)ccc1CCC(O)=O

InChI Key InChIKey=SWUZQDVMRRMTCS-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50227742   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50227742(3-(2-methyl-4-(3-((2-methyl-4-(trifluoromethyl)ben...)
Affinity DataIC50:  126nMAssay Description:Displacement of [3H]-2-methyl-2-(4-{3-{propyl-(5-pyridin-2-yl-thiophene-2-sulfonyl)-amino}-propyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50227742(3-(2-methyl-4-(3-((2-methyl-4-(trifluoromethyl)ben...)
Affinity DataEC50:  345nMAssay Description:Agonist activity at human PPARgamma expressed in CV1 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50227742(3-(2-methyl-4-(3-((2-methyl-4-(trifluoromethyl)ben...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from human PPARalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50227742(3-(2-methyl-4-(3-((2-methyl-4-(trifluoromethyl)ben...)
Affinity DataEC50:  33nMAssay Description:Agonist activity at human PPARdelta expressed in CV1 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50227742(3-(2-methyl-4-(3-((2-methyl-4-(trifluoromethyl)ben...)
Affinity DataEC50:  2.89E+3nMAssay Description:Agonist activity at human PPARalpha expressed in CV1 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50227742(3-(2-methyl-4-(3-((2-methyl-4-(trifluoromethyl)ben...)
Affinity DataIC50:  5nMAssay Description:Displacement of [3H]-2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from human PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed