BDBM50231499 CHEMBL253421::N-(2-{2-[4-(4-cyano-benzyloxy)-phenyl]-5-phenyl-pyrrol-1-yl}-acetyl)-guanidine

SMILES NC(=N)NC(=O)Cn1c(ccc1-c1ccc(OCc2ccc(cc2)C#N)cc1)-c1ccccc1

InChI Key InChIKey=ADLPXDDRQKBSPD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231499   

TargetBeta-secretase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50231499(N-(2-{2-[4-(4-cyano-benzyloxy)-phenyl]-5-phenyl-py...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed