BDBM50232646 CHEMBL254112::N-(2-aminophenyl)-4-((6-bromobenzo[d]thiazol-2-ylamino)methyl)benzamide

SMILES Nc1ccccc1NC(=O)c1ccc(CNc2nc3ccc(Br)cc3s2)cc1

InChI Key InChIKey=UBEDKYNGAVJFEP-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50232646   

TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232646(N-(2-aminophenyl)-4-((6-bromobenzo[d]thiazol-2-yla...)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232646(N-(2-aminophenyl)-4-((6-bromobenzo[d]thiazol-2-yla...)
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibition of HDAC1 in human T24 cells assessed as induction of histone H4 acetylation after 16 hrs relative to MS-275More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed