BDBM50234926 CHEMBL4101945

SMILES CN1CCc2c(C1)cccc2Nc1cnn(C)c(=O)c1Cl

InChI Key InChIKey=YJJYUKCKKSVTAG-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50234926   

TargetBromodomain-containing protein 9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50234926(CHEMBL4101945)
Affinity DataIC50:  2.00E+3nMAssay Description:Displacement of GSK2833930A from human BRD9 incubated for 30 mins in dark by TR-FRET assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50234926(CHEMBL4101945)
Affinity DataIC50:  2.00E+3nMAssay Description:Displacement of GSK2833930A from human BRD9 incubated for 30 mins in dark by TR-FRET assayMore data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50234926(CHEMBL4101945)
Affinity DataIC50:  316nMAssay Description:Displacement of GSK3103956A from FLAG-6 His-Halo tagged human PCAF bromodomain (715 to 831 residues) incubated for 30 mins in dark by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50234926(CHEMBL4101945)
Affinity DataIC50:  300nMAssay Description:Displacement of GSK3103956A from FLAG-6 His-Halo tagged human PCAF bromodomain (715 to 831 residues) incubated for 30 mins in dark by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed