BDBM50237830 CHEMBL3799807

SMILES COc1nc(nc(n1)Nc2ccc3c(c2)cn[nH]3)NCCc4c[nH]c5c4cccc5

InChI Key InChIKey=NSJQROISOSHTBB-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50237830   

TargetSerine/threonine-protein kinase PAK 4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50237830(CHEMBL3799807)
Affinity DataIC50: 790nMAssay Description:Inhibition of recombinant human N-terminal His6/GST-tagged PAK4 (295 to 591 residues) expressed in baculovirus infected Sf21 cells using myelin basic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase PAK 4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50237830(CHEMBL3799807)
Affinity DataIC50: 790nMAssay Description:Inhibition of PAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase PAK 4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50237830(CHEMBL3799807)
Affinity DataIC50: 790nMAssay Description:Inhibition of human PAK4 assessed as enzymatic activity incubated for 20 mins by filter binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase PAK 4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50237830(CHEMBL3799807)
Affinity DataIC50: 790nMAssay Description:Inhibition of N-terminal His-tagged human PAK4 kinase domain (300 to 591 residues) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)