BDBM50238255 CHEMBL3753333

SMILES Cc1noc(C)c1-c1ccc2n(CCN3CCOCC3)c(CCc3ccccc3)nc2c1

InChI Key InChIKey=ZVYCZICBBIUVHC-UHFFFAOYSA-N

Data  2 IC50  2 Kd

PDB links: 3 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50238255   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50238255(CHEMBL3753333)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of BRD4 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50238255(CHEMBL3753333)
Affinity DataKd:  950nMAssay Description:Binding affinity to human BRD4 bromodomain1 by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50238255(CHEMBL3753333)
Affinity DataKd:  320nMAssay Description:Binding affinity to human CBP by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50238255(CHEMBL3753333)
Affinity DataIC50:  240nMAssay Description:Inhibition of CREBBP (unknown origin) by FRET assayMore data for this Ligand-Target Pair