BDBM50240224 CHEMBL4095856

SMILES CN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)Nc2ccc(C)c(NC(=O)c3cccc(c3)-c3cnn(C)c3)c2)CC1

InChI Key InChIKey=WLQMBDLMYOJZCC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50240224   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50240224(CHEMBL4095856)
Affinity DataIC50:  740nMAssay Description:Inhibitory activity was determined against HSV-1 Ribonucleoside diphosphate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50240224(CHEMBL4095856)
Affinity DataIC50:  69nMAssay Description:Inhibition of recombinant human His-tagged CSF1R cytoplasmic domain (538 to 910 residues) expressed in baculovirus expression system using fluorescen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50240224(CHEMBL4095856)
Affinity DataIC50:  1nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50240224(CHEMBL4095856)
Affinity DataIC50:  443nMAssay Description:Inhibition of recombinant human His-tagged CSF1R cytoplasmic domain (538 to 910 residues) expressed in baculovirus expression system using fluorescen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50240224(CHEMBL4095856)
Affinity DataIC50:  337nMAssay Description:Inhibition of recombinant human His-tagged CSF1R cytoplasmic domain (538 to 910 residues) expressed in baculovirus expression system using fluorescen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed