BDBM50241495 CHEMBL4079933

SMILES COc1ccc(CN(CC(=O)N2CCC(N)CC2)c2ccc(cc2)C#N)cc1F

InChI Key InChIKey=RUDSQAKPIYHENP-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50241495   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50241495(CHEMBL4079933)
Affinity DataIC50:  810nMAssay Description:Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50241495(CHEMBL4079933)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of human hERG by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50241495(CHEMBL4079933)
Affinity DataKd:  190nMAssay Description:Binding affinity to LSD1 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed