BDBM50243265 (2S,4R)-N,N-dimethyl-4-(o-tolyloxy)-1,2,3,4-tetrahydronaphthalen-2-amine::CHEMBL488049

SMILES CN(C)[C@@H]1C[C@@H](Oc2ccccc2C)c2ccccc2C1

InChI Key InChIKey=NDHNYVIKBFYSGN-QFBILLFUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243265   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243265((2S,4R)-N,N-dimethyl-4-(o-tolyloxy)-1,2,3,4-tetrah...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of dopamine uptake at human DAT in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243265((2S,4R)-N,N-dimethyl-4-(o-tolyloxy)-1,2,3,4-tetrah...)
Affinity DataIC50:  700nMAssay Description:Inhibition of serotonin uptake at human SERT in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243265((2S,4R)-N,N-dimethyl-4-(o-tolyloxy)-1,2,3,4-tetrah...)
Affinity DataIC50:  430nMAssay Description:Inhibition of norepinephrine uptake at human NET in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed