BDBM50243302 CHEMBL454086::Tetrahydrofuran-2-ylmethyl[4-({[2-(pyridin-2-ylcarbonyl)phenyl}-amino}sulfonyl)phenyl]carbamate

SMILES O=C(Nc1ccc(cc1)S(=O)(=O)Nc1ccccc1C(=O)c1ccccn1)OCC1CCCO1

InChI Key InChIKey=PLUSCNOLGPTWEQ-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50243302   

TargetB1 bradykinin receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243302(Tetrahydrofuran-2-ylmethyl[4-({[2-(pyridin-2-ylcar...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to human bradykinin B1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243302(Tetrahydrofuran-2-ylmethyl[4-({[2-(pyridin-2-ylcar...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to human bradykinin B1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243302(Tetrahydrofuran-2-ylmethyl[4-({[2-(pyridin-2-ylcar...)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of MK-499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243302(Tetrahydrofuran-2-ylmethyl[4-({[2-(pyridin-2-ylcar...)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of MK-499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed