BDBM50244048 (1S,5R)-1-(2,3-dihydro-1H-inden-5-yl)-3-aza-bicyclo[3.1.0]hexane::CHEMBL452543

SMILES C1[C@H]2CNC[C@@]12c1ccc2CCCc2c1

InChI Key InChIKey=JZZRHFYNTMGOKH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50244048   

TargetSodium-dependent serotonin transporter(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50244048((1S,5R)-1-(2,3-dihydro-1H-inden-5-yl)-3-aza-bicycl...)
Affinity DataIC50: 97nMAssay Description:Inhibition of serotonin uptake at SERT in rat brain synaptosomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50244048((1S,5R)-1-(2,3-dihydro-1H-inden-5-yl)-3-aza-bicycl...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of norepinephrine uptake at NET in rat brain synaptosomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50244048((1S,5R)-1-(2,3-dihydro-1H-inden-5-yl)-3-aza-bicycl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dopamine uptake at cloned DAT in rat brain synaptosomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed