BDBM50244477 (Z)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-4-ylmethylene)-tetrahydrofuran-2-yl)methyl 4-(dimethylamino)benzoate::CHEMBL488671

SMILES CN(C)c1ccc(cc1)C(=O)OCC1(CO)C\C(=C\c2ccncc2)C(=O)O1

InChI Key InChIKey=PUONMCPYNHSWMF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50244477   

TargetRas guanyl-releasing protein 3(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244477((Z)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-4-ylmethyl...)
Affinity DataKi:  2.36E+3nMAssay Description:Displacement of [3H]PDBu from RasGRP3 expressed in cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244477((Z)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-4-ylmethyl...)
Affinity DataKi:  3.32E+4nMAssay Description:Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed