BDBM50244630 CHEMBL454105::N-(2-methyl-5-((3-(trifluoromethyl)phenyl)carbamoyl)phenyl)nicotinamide

SMILES Cc1ccc(cc1NC(=O)c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=NZCFIQMFQCSIJL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50244630   

TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50244630(CHEMBL454105 | N-(2-methyl-5-((3-(trifluoromethyl)...)
Affinity DataIC50:  32nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed