BDBM50244928 (E)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-3-ylmethylene)-tetrahydrofuran-2-yl)methyl 4-(dimethylamino)benzoate::CHEMBL472183

SMILES CN(C)c1ccc(cc1)C(=O)OCC1(CO)C\C(=C/c2cnc3ccccc3c2)C(=O)O1

InChI Key InChIKey=DEQHLCSNLCBPHA-UDWIEESQSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50244928   

TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244928((E)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-3-ylmethy...)
Affinity DataKi:  137nMAssay Description:Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244928((E)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-3-ylmethy...)
Affinity DataKi:  755nMAssay Description:Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed