BDBM50245851 Spiclomazine

SMILES Clc1ccc2Sc3ccccc3N(CCCN3CCC4(CC3)NC(=O)CS4)c2c1

InChI Key InChIKey=CFOYBMUYCBSDAL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50245851   

TargetBeta-secretase 1(Homo sapiens (Human))
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50245851(Spiclomazine)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of human BACE-1 preincubated for 1 hr followed by substrate addition measured after 60 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed