BDBM50247701 2-[1'-Phenyl-3'-(4-ethoxyphenyl)-2'-propenylidene]hydrazine-3-methyl-4(3H)-quinazolinone::CHEMBL454378

SMILES CCOc1ccc(CC=C(N=Nc2nc3ccccc3c(=O)n2C)c2ccccc2)cc1

InChI Key InChIKey=KRONFQIWHICXAA-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50247701   

TargetAmine oxidase [flavin-containing] A(Rat)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50247701(2-[1'-Phenyl-3'-(4-ethoxyphenyl)-2'-propenylidene]...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of MAO-A in rat liver homogenate after 60 mins by residual activity plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50247701(2-[1'-Phenyl-3'-(4-ethoxyphenyl)-2'-propenylidene]...)
Affinity DataKi:  3.06E+4nMAssay Description:Inhibition of MAO-B in rat liver homogenate after 60 mins by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50247701(2-[1'-Phenyl-3'-(4-ethoxyphenyl)-2'-propenylidene]...)
Affinity DataKi:  8.01E+4nMAssay Description:Inhibition of MAO-A in rat liver homogenate after 60 mins by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50247701(2-[1'-Phenyl-3'-(4-ethoxyphenyl)-2'-propenylidene]...)
Affinity DataIC50: 4.29E+5nMAssay Description:Inhibition of MAO-B in rat liver homogenate after 60 mins by residual activity plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed