BDBM50247703 2-[(3-(4-Methylphenyl)-5'-thienyl-2'-pyrazoline-1-yl]-3-methyl-4(3H)-quinazolinone::CHEMBL454172

SMILES Cc1ccc(cc1)C1=NN(C(C1)c1cccs1)c1nc2ccccc2c(=O)n1C

InChI Key InChIKey=QVXMEQFRTCVWEH-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50247703   

TargetAmine oxidase [flavin-containing] B(Rat)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50247703(2-[(3-(4-Methylphenyl)-5'-thienyl-2'-pyrazoline-1-...)
Affinity DataIC50: 7.08E+4nMAssay Description:Inhibition of MAO-B in rat liver homogenate after 60 mins by residual activity plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50247703(2-[(3-(4-Methylphenyl)-5'-thienyl-2'-pyrazoline-1-...)
Affinity DataKi:  9.07E+4nMAssay Description:Inhibition of MAO-B in rat liver homogenate after 60 mins by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50247703(2-[(3-(4-Methylphenyl)-5'-thienyl-2'-pyrazoline-1-...)
Affinity DataKi:  1.30E+5nMAssay Description:Inhibition of MAO-A in rat liver homogenate after 60 mins by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50247703(2-[(3-(4-Methylphenyl)-5'-thienyl-2'-pyrazoline-1-...)
Affinity DataIC50: 4.15E+5nMAssay Description:Inhibition of MAO-A in rat liver homogenate after 60 mins by residual activity plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed