BDBM50247769 2-[(3-Phenyl-5'-(4-methoxyphenyl)-2'-pyrazoline-1-yl]-3-methyl-4(3H)-quinazolinone::CHEMBL460733

SMILES COc1ccc(cc1)C1CC(=NN1c1nc2ccccc2c(=O)n1C)c1ccccc1

InChI Key InChIKey=ZWLSGCSOGXPGCN-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50247769   

TargetAmine oxidase [flavin-containing] A(Rat)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50247769(2-[(3-Phenyl-5'-(4-methoxyphenyl)-2'-pyrazoline-1-...)
Affinity DataKi:  1.03E+3nMAssay Description:Inhibition of MAO-A in rat liver homogenate after 60 mins by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50247769(2-[(3-Phenyl-5'-(4-methoxyphenyl)-2'-pyrazoline-1-...)
Affinity DataIC50: 4.51E+3nMAssay Description:Inhibition of MAO-A in rat liver homogenate after 60 mins by residual activity plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50247769(2-[(3-Phenyl-5'-(4-methoxyphenyl)-2'-pyrazoline-1-...)
Affinity DataKi:  9.90E+3nMAssay Description:Inhibition of MAO-B in rat liver homogenate after 60 mins by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50247769(2-[(3-Phenyl-5'-(4-methoxyphenyl)-2'-pyrazoline-1-...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of MAO-B in rat liver homogenate after 60 mins by residual activity plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed