BDBM50248217 1-(4-Methoxyphenylsulfonamido)-3-morpholinopropan-2-yl dihydrogen phosphate::CHEMBL473552::HEA derivative, 7a

SMILES COc1ccc(cc1)S(=O)(=O)NCC(CN1CCOCC1)OP(O)(O)=O

InChI Key InChIKey=KQRLPNNZQJZXAV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50248217   

TargetUDP-N-acetylmuramate--L-alanine ligase(Escherichia coli)
University Of Ljubljana

LigandPNGBDBM50248217(1-(4-Methoxyphenylsulfonamido)-3-morpholinopropan-...)
Affinity DataIC50:  4.90E+5nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVancomycin/teicoplanin A-type resistance protein VanA(Enterococcus faecium)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50248217(1-(4-Methoxyphenylsulfonamido)-3-morpholinopropan-...)
Affinity DataIC50:  2.24E+5nMAssay Description:Inhibition of Enterococcus faecium VanA by pyruvate kinase/lactate dehydrogenase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Escherichia coli)
University Of Ljubljana

LigandPNGBDBM50248217(1-(4-Methoxyphenylsulfonamido)-3-morpholinopropan-...)
Affinity DataIC50:  5.30E+5nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase(Staphylococcus aureus)
University Of Ljubljana

LigandPNGBDBM50248217(1-(4-Methoxyphenylsulfonamido)-3-morpholinopropan-...)
Affinity DataIC50:  6.00E+3nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed