BDBM50248218 1-(4-Fluorophenylsulfonamido)-3-morpholinopropan-2-yl dihydrogen phosphate::CHEMBL473752::HEA derivative, 7b
SMILES OP(O)(=O)OC(CNS(=O)(=O)c1ccc(F)cc1)CN1CCOCC1
InChI Key InChIKey=PQONZGNIVZDUAK-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50248218
Affinity DataIC50: 7.90E+5nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
TargetVancomycin/teicoplanin A-type resistance protein VanA(Enterococcus faecium)
University Of Ljubljana
Curated by ChEMBL
University Of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 2.90E+5nMAssay Description:Inhibition of Enterococcus faecium VanA by pyruvate kinase/lactate dehydrogenase coupled assayMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Escherichia coli)
University of Ljubljana
University of Ljubljana
Affinity DataIC50: 2.70E+5nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase(Staphylococcus aureus)
University of Ljubljana
University of Ljubljana
Affinity DataIC50: 1.20E+5nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair