BDBM50248628 CHEMBL4072496

SMILES NC(=O)c1[nH]cc(c1Cl)-c1ccncc1

InChI Key InChIKey=PGLBZRZEQTVNDN-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248628   

TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50248628(CHEMBL4072496)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant full length His-tagged human CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50248628(CHEMBL4072496)
Affinity DataIC50:  7nMAssay Description:Inhibition of full length recombinant human His-tagged CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...More data for this Ligand-Target Pair