BDBM50249193 (15R)-15-methyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6.2.0^{2,7}.0^{9,14}]hexadeca-2,4,6,9(14),10,12-hexaene-15-carboxamide::CHEMBL514646

SMILES C[C@]1(CC2c3ccccc3C1c1ccccc21)C(=O)Nc1nccs1

InChI Key InChIKey=QYEYUIJWYCBKBG-WIXQSORDSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50249193   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50249193((15R)-15-methyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6...)
Affinity DataKi:  1.30nMAssay Description:Displacement of FITC-dexamethasone from human recombinant glucocorticoid receptor alpha by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50249193((15R)-15-methyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6...)
Affinity DataKi:  147nMAssay Description:Displacement of radioligand from progesterone receptor by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50249193((15R)-15-methyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6...)
Affinity DataKi:  7.40E+3nMAssay Description:Displacement of radioligand from androgen receptor by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50249193((15R)-15-methyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6...)
Affinity DataKi:  1.50E+4nMAssay Description:Displacement of radioligand from estrogen receptor alpha by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50249193((15R)-15-methyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6...)
Affinity DataEC50:  115nMAssay Description:Transrepression activity at GR in PMA-stimulated human A549 cells assessed as inhibition of AP1 response element-induced luciferase reporter gene act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed