BDBM50249525 CHEMBL470532::N-((5-hydroxy-1,3,3-trimethylcyclohexyl)methyl)dibenzo[b,d]furan-2-sulfonamide

SMILES CC1(C)CC(O)CC(C)(CNS(=O)(=O)c2ccc3oc4ccccc4c3c2)C1

InChI Key InChIKey=SOAHRORIZWYEIR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249525   

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50249525(N-((5-hydroxy-1,3,3-trimethylcyclohexyl)methyl)dib...)
Affinity DataIC50: 440nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximity assay in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50249525(N-((5-hydroxy-1,3,3-trimethylcyclohexyl)methyl)dib...)
Affinity DataIC50: 850nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximity assay in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed