BDBM50249884 CHEMBL523155::[2-(Hydroxymethyl)-4-(methylethylidene)-5-oxo-2-2,3-dihydrofuryl]methyl 2-(4-[2-(4-Methylphenyl)ethynyl]phenoxy)acetate

SMILES CC(C)=C1CC(CO)(COC(=O)COc2ccc(C#Cc3ccc(C)cc3)cc2)OC1=O

InChI Key InChIKey=LUDKZCXHZJRUAZ-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50249884   

TargetProtein kinase C alpha type(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249884BDBM50249884([2-(Hydroxymethyl)-4-(methylethylidene)-5-oxo-2-2,...)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]PDBu form human PKCalpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249884BDBM50249884([2-(Hydroxymethyl)-4-(methylethylidene)-5-oxo-2-2,...)
Affinity DataKi:  46nMAssay Description:Displacement of [3H]PDBu form human PKCdelta in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249884BDBM50249884([2-(Hydroxymethyl)-4-(methylethylidene)-5-oxo-2-2,...)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]PDBu form human PKCdelta in presence of plasma membrane lipid mimetic mixtureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C gamma type(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249884BDBM50249884([2-(Hydroxymethyl)-4-(methylethylidene)-5-oxo-2-2,...)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]PDBu form human PKCgamma in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249884BDBM50249884([2-(Hydroxymethyl)-4-(methylethylidene)-5-oxo-2-2,...)
Affinity DataKi:  76nMAssay Description:Displacement of [3H]PDBu form human PKCbeta in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249884BDBM50249884([2-(Hydroxymethyl)-4-(methylethylidene)-5-oxo-2-2,...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]PDBu form human PKCbeta in presence of plasma membrane lipid mimetic mixtureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C gamma type(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249884BDBM50249884([2-(Hydroxymethyl)-4-(methylethylidene)-5-oxo-2-2,...)
Affinity DataKi:  140nMAssay Description:Displacement of [3H]PDBu form human PKCgamma in presence of plasma membrane lipid mimetic mixtureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249884BDBM50249884([2-(Hydroxymethyl)-4-(methylethylidene)-5-oxo-2-2,...)
Affinity DataKi:  147nMAssay Description:Displacement of [3H]PDBu form human PKCepsilon in presence of plasma membrane lipid mimetic mixtureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249884BDBM50249884([2-(Hydroxymethyl)-4-(methylethylidene)-5-oxo-2-2,...)
Affinity DataKi:  165nMAssay Description:Displacement of [3H]PDBu form human PKCalpha in presence of plasma membrane lipid mimetic mixtureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249884BDBM50249884([2-(Hydroxymethyl)-4-(methylethylidene)-5-oxo-2-2,...)
Affinity DataKi:  268nMAssay Description:Displacement of [3H]PDBu form human PKCepsilon in presence of phosphatidylserineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed