BDBM50252056 CHEMBL519134::Ethyl 2-oxo-2-{3-[(pyridine-3-carbonyl)-amino]-phenyl}-ethyl trithiocarbonate

SMILES CCSC(=S)SCC(=O)c1cccc(NC(=O)c2cccnc2)c1

InChI Key InChIKey=ODEJQVXPGWPXQR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50252056   

TargetHistone deacetylase 6(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252056(Ethyl 2-oxo-2-{3-[(pyridine-3-carbonyl)-amino]-phe...)
Affinity DataIC50: 38nMAssay Description:Inhibition of recombinant HDAC6 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252056(Ethyl 2-oxo-2-{3-[(pyridine-3-carbonyl)-amino]-phe...)
Affinity DataIC50: 388nMAssay Description:Inhibition of recombinant HDAC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed