BDBM50252782 CHEMBL493671::N-Cyclopropyl-4-methyl-3-(1-((S)-2,2,2-trifluoro-1-methylethoxy)-6-phthalazinyl)benzamide

SMILES C[C@H](Oc1nncc2cc(ccc12)-c1cc(ccc1C)C(=O)NC1CC1)C(F)(F)F

InChI Key InChIKey=XANMCBRIKIVXBI-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50252782   

TargetTyrosine-protein kinase Lyn(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(N-Cyclopropyl-4-methyl-3-(1-((S)-2,2,2-trifluoro-1...)
Affinity DataIC50: 954nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(N-Cyclopropyl-4-methyl-3-(1-((S)-2,2,2-trifluoro-1...)
Affinity DataIC50: 1nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252782(N-Cyclopropyl-4-methyl-3-(1-((S)-2,2,2-trifluoro-1...)
Affinity DataIC50: 2.68E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(N-Cyclopropyl-4-methyl-3-(1-((S)-2,2,2-trifluoro-1...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252782(N-Cyclopropyl-4-methyl-3-(1-((S)-2,2,2-trifluoro-1...)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of cKitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(N-Cyclopropyl-4-methyl-3-(1-((S)-2,2,2-trifluoro-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(N-Cyclopropyl-4-methyl-3-(1-((S)-2,2,2-trifluoro-1...)
Affinity DataIC50: 7.77E+3nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(N-Cyclopropyl-4-methyl-3-(1-((S)-2,2,2-trifluoro-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed