BDBM50252782 CHEMBL493671::N-Cyclopropyl-4-methyl-3-(1-((S)-2,2,2-trifluoro-1-methylethoxy)-6-phthalazinyl)benzamide

SMILES C[C@H](Oc1nncc2cc(ccc12)-c1cc(ccc1C)C(=O)NC1CC1)C(F)(F)F

InChI Key InChIKey=XANMCBRIKIVXBI-ZDUSSCGKSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50252782   

TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(CHEMBL493671 | N-Cyclopropyl-4-methyl-3-(1-((S)-2,...)
Affinity DataIC50:  954nMAssay Description:Inhibition of Lyn (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(CHEMBL493671 | N-Cyclopropyl-4-methyl-3-(1-((S)-2,...)
Affinity DataIC50:  1nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(CHEMBL493671 | N-Cyclopropyl-4-methyl-3-(1-((S)-2,...)
Affinity DataIC50:  2.68E+3nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(CHEMBL493671 | N-Cyclopropyl-4-methyl-3-(1-((S)-2,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(CHEMBL493671 | N-Cyclopropyl-4-methyl-3-(1-((S)-2,...)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of cKit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(CHEMBL493671 | N-Cyclopropyl-4-methyl-3-(1-((S)-2,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(CHEMBL493671 | N-Cyclopropyl-4-methyl-3-(1-((S)-2,...)
Affinity DataIC50:  7.77E+3nMAssay Description:Inhibition of JNK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(CHEMBL493671 | N-Cyclopropyl-4-methyl-3-(1-((S)-2,...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed