BDBM50253153 CHEMBL495330::N-Cyclopropyl-4-methyl-3-(1-phenyl-6-phthalazinyl)benzamide

SMILES Cc1ccc(cc1-c1ccc2c(nncc2c1)-c1ccccc1)C(=O)NC1CC1

InChI Key InChIKey=LQXUFIFTFVOCHC-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50253153   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253153(CHEMBL495330 | N-Cyclopropyl-4-methyl-3-(1-phenyl-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253153(CHEMBL495330 | N-Cyclopropyl-4-methyl-3-(1-phenyl-...)
Affinity DataIC50:  6.29E+3nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253153(CHEMBL495330 | N-Cyclopropyl-4-methyl-3-(1-phenyl-...)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253153(CHEMBL495330 | N-Cyclopropyl-4-methyl-3-(1-phenyl-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253153(CHEMBL495330 | N-Cyclopropyl-4-methyl-3-(1-phenyl-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253153(CHEMBL495330 | N-Cyclopropyl-4-methyl-3-(1-phenyl-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JNK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253153(CHEMBL495330 | N-Cyclopropyl-4-methyl-3-(1-phenyl-...)
Affinity DataIC50:  149nMAssay Description:Inhibition of cKit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed