BDBM50253543 (+)-(S)-Ethyl-[2-hydroxy-2-[1-(4-methoxy)phenyl-2-methyl-5-(4-methylsulfonyl)phenyl-1H-pyrrol-3-yl]]acetate::CHEMBL495318

SMILES CCOC(=O)[C@@H](O)c1cc(-c2ccc(cc2)S(C)(=O)=O)n(c1C)-c1ccc(OC)cc1

InChI Key InChIKey=SYMLRSRHBJWTTH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50253543   

TargetProstaglandin G/H synthase 2(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50253543((+)-(S)-Ethyl-[2-hydroxy-2-[1-(4-methoxy)phenyl-2-...)
Affinity DataIC50: 79nMAssay Description:Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production after 15 mins by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50253543((+)-(S)-Ethyl-[2-hydroxy-2-[1-(4-methoxy)phenyl-2-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in arachidonic acid-stimulated mouse J774 cells assessed as inhibition of PGE2 production after 15 mins by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed