BDBM50253566 (+/-)-Ethyl-[2-ethoxy-2-[-2-methyl-5-(4-methylsulfonyl)-phenyl-1-phenyl-1H-pyrrol-3-yl]]acetate::CHEMBL522166

SMILES CCOC(C(=O)OCC)c1cc(-c2ccc(cc2)S(C)(=O)=O)n(c1C)-c1ccccc1

InChI Key InChIKey=RSDWFRPCZDPSCL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50253566   

TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50253566((+/-)-Ethyl-[2-ethoxy-2-[-2-methyl-5-(4-methylsulf...)
Affinity DataIC50:  180nMAssay Description:Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production after 15 mins by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50253566((+/-)-Ethyl-[2-ethoxy-2-[-2-methyl-5-(4-methylsulf...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX1 in arachidonic acid-stimulated mouse J774 cells assessed as inhibition of PGE2 production after 15 mins by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed