BDBM50253566 (+/-)-Ethyl-[2-ethoxy-2-[-2-methyl-5-(4-methylsulfonyl)-phenyl-1-phenyl-1H-pyrrol-3-yl]]acetate::CHEMBL522166
SMILES CCOC(C(=O)OCC)c1cc(-c2ccc(cc2)S(C)(=O)=O)n(c1C)-c1ccccc1
InChI Key InChIKey=RSDWFRPCZDPSCL-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50253566
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production after 15 mins by radioimmunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX1 in arachidonic acid-stimulated mouse J774 cells assessed as inhibition of PGE2 production after 15 mins by radioimmunoassayMore data for this Ligand-Target Pair