BDBM50254640 CHEMBL482379::N-(2,5-dimethoxyphenylsulfonyl)-2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)acetamide

SMILES COc1ccc(OC)c(S(=O)(=O)NC(=O)COc2cccc3[nH]cc(Sc4ccc5ccccc5c4)c23)c1

InChI Key InChIKey=GLNIFIRXDUKUCS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254640   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254640BDBM50254640(N-(2,5-dimethoxyphenylsulfonyl)-2-(3-(naphthalen-2...)
Affinity DataIC50: 1.20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254640BDBM50254640(N-(2,5-dimethoxyphenylsulfonyl)-2-(3-(naphthalen-2...)
Affinity DataIC50: 134nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed