BDBM50254702 4-cyclopropyl-N-((tetrahydro-2H-pyran-4-yl)methyl)-6-(3-(trifluoromethoxy)phenylamino)nicotinamide::CHEMBL520413

SMILES FC(F)(F)Oc1cccc(Nc2cc(C3CC3)c(cn2)C(=O)NCC2CCOCC2)c1

InChI Key InChIKey=QMSZYSVYDVBLRN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50254702   

TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254702(4-cyclopropyl-N-((tetrahydro-2H-pyran-4-yl)methyl)...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254702(4-cyclopropyl-N-((tetrahydro-2H-pyran-4-yl)methyl)...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254702(4-cyclopropyl-N-((tetrahydro-2H-pyran-4-yl)methyl)...)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254702(4-cyclopropyl-N-((tetrahydro-2H-pyran-4-yl)methyl)...)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed