BDBM50256929 CHEMBL514511::N1-(2-aminophenyl)-N4-(3-(methyl(4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)terephthalamide

SMILES CN(C(=O)c1ccc(cc1)C(=O)Nc1ccccc1N)c1cccc(Nc2nccc(n2)-c2cccnc2)c1

InChI Key InChIKey=CECVMCWVJXADBQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50256929   

TargetHistone deacetylase 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50256929(N1-(2-aminophenyl)-N4-(3-(methyl(4-(pyridin-3-yl)p...)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of human recombinant HDAC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50256929(N1-(2-aminophenyl)-N4-(3-(methyl(4-(pyridin-3-yl)p...)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of VEGFR2 by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50256929(N1-(2-aminophenyl)-N4-(3-(methyl(4-(pyridin-3-yl)p...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of PDGFRbeta by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50256929(N1-(2-aminophenyl)-N4-(3-(methyl(4-(pyridin-3-yl)p...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of wild-type c-Abl by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50256929(N1-(2-aminophenyl)-N4-(3-(methyl(4-(pyridin-3-yl)p...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC6 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed