BDBM50257751 CHEMBL494326::N-benzyl-6-bromoquinazolin-4-amine::cid_720645

SMILES Brc1ccc2ncnc(NCc3ccccc3)c2c1

InChI Key InChIKey=CRIVWOZDTPNCTP-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50257751   

TargetXylosyl- and glucuronyltransferase LARGE1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50257751(CHEMBL494326 | N-benzyl-6-bromoquinazolin-4-amine ...)
Affinity DataEC50:  3.34E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM50257751(CHEMBL494326 | N-benzyl-6-bromoquinazolin-4-amine ...)
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of Huntingtin protein (unknown origin) aggregation by yeast based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM50257751(CHEMBL494326 | N-benzyl-6-bromoquinazolin-4-amine ...)
Affinity DataIC50:  6.13E+3nMAssay Description:Inhibition of Huntingtin protein aggregation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed