BDBM50258405 6-((3',4'-dichlorobiphenyl-3-yl)methylamino)-9-(3-hydroxypropyl)-9H-purine-2-carbonitrile::CHEMBL495017

SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccc(Cl)c(Cl)c3)nc(nc12)C#N

InChI Key InChIKey=XDKICXYZMQHSCW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50258405   

TargetCathepsin B(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50258405(6-((3',4'-dichlorobiphenyl-3-yl)methylamino)-9-(3-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50258405(6-((3',4'-dichlorobiphenyl-3-yl)methylamino)-9-(3-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of California

Curated by ChEMBL
LigandPNGBDBM50258405(6-((3',4'-dichlorobiphenyl-3-yl)methylamino)-9-(3-...)
Affinity DataIC50:  900nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed